c-MET anticorps (C-Term)
Aperçu rapide pour c-MET anticorps (C-Term) (ABIN2854819)
Antigène
Voir toutes c-MET (MET) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Chimpanzé
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Réactivité croisée (Details)
- Chimpanzee (100 %)
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Attributs du produit
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Rabbit Polyclonal antibody to MET (met proto-oncogene (hepatocyte growth factor receptor))
c-Met antibody [C3], C-term -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human c-Met. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*
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Commentaires
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Positive Control: HeLaS3
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- c-MET (MET) (Met Proto-Oncogene (MET))
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Autre désignation
- C-Met
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Sujet
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The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Membrane, Single-pass type I membrane protein -
Poids moléculaire
- 156 kDa
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ID gène
- 4233
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Pathways
- Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
Antigène
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