c-MET anticorps (Catalytic Domain)

N° du produit ABIN387741

Cet anticorps anti-c-MET Monoclonal Souris (Clone 4AT44) (ABIN387741) détecte spécifiquement c-MET dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour c-MET anticorps (Catalytic Domain) (ABIN387741)

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp c-MET est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4AT44

Détail du produit anti-c-MET anticorps

Épitope: Catalytic Domain

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This monoclonal antibody is generated from mice immunized with purified recombinant protein encoding the catalytic domain of human Met.

Isotype: IgG1

Information d'application

Indications d'application: IF: 1:100. WB: 1:8000. IHC-P: 1:50~100. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Détails sur c-MET

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Autre désignation: MET/HGFR

Sujet: The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 155541

ID gène: 4233

NCBI Accession: NP_000236, NP_001120972

UniProt: P08581

Pathways: Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor