IL1R2 anticorps

N° du produit ABIN2856630

Détail du produit anti-IL1R2 anticorps

Antigène: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL1R2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to IL1 receptor 2 (interleukin 1 receptor, type II)
IL1 Receptor 2 antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human IL1 Receptor 2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , mouse brain , rat brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur IL1R2

Antigène: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Autre désignation: interleukin 1 receptor type 2 (IL1R2 Produits)

Synonymes: anticorps CD121b, anticorps CDw121b, anticorps IL-1R-2, anticorps IL-1RT-2, anticorps IL-1RT2, anticorps IL1R2c, anticorps IL1RB, anticorps Il1r-2, anticorps IL-1R2, anticorps interleukin 1 receptor type 2, anticorps interleukin 1 receptor, type II, anticorps interleukin-like, anticorps IL1R2, anticorps Il1r2, anticorps KK34

Sujet: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.

Cellular Localization: Membrane, Single-pass type I membrane protein

Poids moléculaire: 45 kDa

ID gène: 7850

UniProt: P27930

Pathways: Signalisation NF-kappaB