IL1R2 anticorps (AA 20-320)

N° du produit ABIN7156749

Détail du produit anti-IL1R2 anticorps

Antigène: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Épitope: AA 20-320

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL1R2 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Interleukin-1 receptor type 2 protein (20-320AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IL1R2

Antigène: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Autre désignation: IL1R2 (IL1R2 Produits)

Synonymes: anticorps CD121b, anticorps CDw121b, anticorps IL-1R-2, anticorps IL-1RT-2, anticorps IL-1RT2, anticorps IL1R2c, anticorps IL1RB, anticorps Il1r-2, anticorps IL-1R2, anticorps interleukin 1 receptor type 2, anticorps interleukin 1 receptor, type II, anticorps interleukin-like, anticorps IL1R2, anticorps Il1r2, anticorps KK34

Sujet:

Background: Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Aliases: IL1 Receptor II antibody, Antigen CDw121b antibody, CD121 antibody, CD121 antigen-like family member B antibody, CD121b antibody, CD121B Antigen antibody, CDw121b antibody, IL 1 type II receptor antibody, IL-1R-2 antibody, IL-1R-beta antibody, IL-1R2 antibody, IL-1RT-2 antibody, IL-1RT2 antibody, IL1R Beta antibody, Il1r-2 antibody, IL1R2 antibody, IL1R2_HUMAN antibody, IL1R2c antibody, IL1RB antibody, Interleukin 1 receptor type II variant 3 antibody, Interleukin 1 receptor, beta, type II antibody, Interleukin 1 receptor, type II antibody, Interleukin-1 receptor beta antibody, Interleukin-1 receptor type 2 antibody, Interleukin-1 receptor type II antibody, MGC137383 antibody, MGC47725 antibody, OTTHUMP00000207969 antibody, p68 antibody, Type II interleukin-1 receptor, beta antibody

UniProt: P27930

Pathways: Signalisation NF-kappaB