Collagen IV anticorps

N° du produit ABIN289410

Détail du produit anti-Collagen IV anticorps

Antigène: Collagen IV (COL4) (Collagen, Type IV (COL4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Collagen IV est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Affinity purified Rabbit polyclonal Collagen Type IV antibody
Bioactivity: Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues

Purification: Affinity chromatography purified

Stérilité: Filtered

Immunogène: Collagen type IV antibody was raised in rabbit using collagen type IV from human and bovine placenta as the immunogen.

Information d'application

Indications d'application: ELISA: 1:5,000-1:20,000, IHC: 1:50-1:200, WB: 1:500-1:5,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Sterile filtered liquid in 0.125 M Na5 5 7, pH 8.0, with 0.075 NaCl, 0.005 EDTA, and 0.01 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Références pour anticorps anti-Collagen IV (ABIN289410)

Tane, Dhar, Roy, Pinheiro, Ohira, Roy: "Effect of excess synthesis of extracellular matrix components by trabecular meshwork cells: possible consequence on aqueous outflow." dans: Experimental eye research, Vol. 84, Issue 5, pp. 832-42, (2007) (PubMed).

Détails sur Collagen IV

Antigène: Collagen IV (COL4) (Collagen, Type IV (COL4))

Autre désignation: Collagen Type IV (COL4 Produits)

Synonymes: anticorps collagen, type IV, anticorps Let-2

Sujet: Collagen is a group of naturally occurring proteins found, in nature, exclusively in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. Type-IV collagen is a type of collagen found primarily in the basal lamina. The C-terminus domain is not removed in post-translational processing, and the fibers link head-to-head, rather than in parallel. Also, type-IV lacks the regular glycine in every third residue necessary for the tight, collagen helix.