SCN5A anticorps (AA 1548-1558)

N° du produit ABIN290512

Détail du produit anti-SCN5A anticorps

Antigène: SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))

Épitope: AA 1548-1558

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN5A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Human SCN5A / Nav1.5. This antibody is expected to recognise all reported isoforms (NP_932173.1, NP_000326.2, NP_001092874.1, NP_001092875.1).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bat, Bovine, Dog, Horse, Pig, Opossum (91%) Turkey, Chicken, Pufferfish, Slime mold (82%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-ETDDQSPEKIN from an internal region of human SCN5A / Nav1.5 (NP_932173.1, NP_000326.2, NP_001092874.1, NP_001092875.1, NP_001153632.1, NP_001153633.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bat, Bovine, Dog, Horse, Pig, Opossum (91%), Turkey, Chicken, Pufferfish, Slime mold (82%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (5 - 10 μg/mL), Peptide-ELISA (1:32000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5-10 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur SCN5A

Antigène: SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))

Autre désignation: SCN5A / Nav1.5 (SCN5A Produits)

Synonymes: anticorps Nav1.5, anticorps Nav1.5c, anticorps SkM1, anticorps SkM2, anticorps mH1, anticorps CDCD2, anticorps CMD1E, anticorps CMPD2, anticorps HB1, anticorps HB2, anticorps HBBD, anticorps HH1, anticorps ICCD, anticorps IVF, anticorps LQT3, anticorps PFHB1, anticorps SSS1, anticorps VF1, anticorps SCAL, anticorps sodium voltage-gated channel alpha subunit 5, anticorps sodium channel, voltage-gated, type V, alpha, anticorps SCN5A, anticorps Scn5a

Sujet: Name/Gene ID: SCN5A
Subfamily: Sodium channel - voltage-gated
Family: Ion Channel

Synonyms: SCN5A, CDCD2, CMPD2, HB1, HB2, HH1, HBBD, Nav1.5, IVF, RSKM2X, SCAL, Scn2x, LQT3, SSS1, MH1, VF1, PFHB1, RATRSKM2X, SkM2, CMD1E, ICCD, RH1, RSkM2

ID gène: 6331

NCBI Accession: NP_932173, NP_000326, NP_001092874, NP_001092875, NP_001153632, NP_001153633

UniProt: Q14524