ATR anticorps (Internal Region)

N° du produit ABIN292420

Détail du produit anti-ATR anticorps

Antigène: ATR (ATR serine/threonine kinase (ATR))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Chien, Singe, Xenopus laevis, Poisson

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATR est non-conjugé

Application: ELISA, Western Blotting (WB)

Specificité: A BLAST analysis was used to suggest cross- reactivity with ATR from human, mouse, rat, monkey, dog, fish and Xenopus sources based on a 100 % homology with the immunizing sequence. Cross-reactivity with ATR from other sources has not been determined

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide corresponding to an internal region of human ATR protein.

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: ELISA (1:15000 - 1:70000), WB (1:1000 - 1:5000)

Usage: This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 301 kD in size corresponding to ATR by western blotting in the appropriate cell lysate or extract. Lysates from HeLa, U2OS, RAW264.7 or HEK293 cells are suggested for western blotting. ATR is ubiquitously expressed, with highest expression levels in the testes. Note that isoform 2 is found in pancreas, placenta and liver but not in heart, testis and ovary.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride,  pH 7.2, 0.01 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur ATR

Antigène: ATR (ATR serine/threonine kinase (ATR))

Autre désignation: ATR (ATR Produits)

Synonymes: anticorps FCTCS, anticorps FRP1, anticorps MEC1, anticorps SCKL, anticorps SCKL1, anticorps ATR serine/threonine kinase, anticorps ataxia telangiectasia and Rad3 related, anticorps ATR, anticorps Atr

Sujet: Name/Gene ID: ATR
Subfamily: PI3/PI4
Family: Protein Kinase

Synonyms: ATR, FRAP-related protein-1, FCTCS, SCKL1, MEC1, Protein kinase ATR, Rad3 related protein, SCKL, FRAP-related protein 1, FRP1

ID gène: 545

UniProt: Q13535

Pathways: Positive Regulation of Response to DNA Damage Stimulus