Neuregulin 1 anticorps (AA 20-241)

N° du produit ABIN6213942

Détail du produit anti-Neuregulin 1 anticorps

Antigène: Neuregulin 1 (NRG1)

Épitope: AA 20-241

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neuregulin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: SGKKPESAAG SQSPALPPRL KEMKSQESAA GSKLVLRCET SSEYSSLRFK WFKNGNELNR KNKPQNIKIQ KKPGKSELRI NKASLADSGE YMCKVISKLG NDSASANITI VESNEIITGM PASTEGAYVS SESPIRISVS TEGANTSSST STSTTGTSHL VKCAEKEKTF CVNGGECFMV KDLSNPSRYL CKCPNEFTGD RCQNYVMASF YSTSTPFLSL PE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 20-241 of human NRG1 (NP_039252.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Neuregulin 1

Antigène: Neuregulin 1 (NRG1)

Autre désignation: NRG1 (NRG1 Produits)

Synonymes: anticorps 6030402G23Rik, anticorps ARIA, anticorps D230005F13Rik, anticorps GGF, anticorps GGFII, anticorps HRG, anticorps HRGalpha, anticorps Hgl, anticorps NDF, anticorps SMDF, anticorps GGF2, anticorps HGL, anticorps HRG1, anticorps HRGA, anticorps MST131, anticorps NRG-1, anticorps heregulin, anticorps nrg1-A, anticorps pro-neuregulin-1, anticorps NRG1, anticorps wu:fm70e01, anticorps DKFZp459A1838, anticorps neuregulin 1, anticorps histidine rich glycoprotein, anticorps neuregulin 1 L homeolog, anticorps Nrg1, anticorps NRG1, anticorps HRG, anticorps nrg1.L, anticorps nrg1

Sujet: The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).,NRG1,ARIA,GGF,GGF2,HGL,HRG,HRG1,HRGA,MST131,MSTP131,NDF,NRG1-IT2,SMDF,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Neuroscience,Cell Type Marker,Oligodendrocyte marker,NRG1

Poids moléculaire: 26 kDa/31 kDa/45- 50 kDa/65-71 kDa

ID gène: 3084

UniProt: Q02297

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation