GADD45A anticorps (AA 1-165)

N° du produit ABIN3022564

Détail du produit anti-GADD45A anticorps

Antigène: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Épitope: AA 1-165

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADD45A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPER

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human GADD45A (NP_001915.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GADD45A

Antigène: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Autre désignation: GADD45A (GADD45A Produits)

Synonymes: anticorps MGC53491, anticorps zgc:91795, anticorps gadd45a, anticorps GADD45A, anticorps ddit1, anticorps gadd45, anticorps GADD45, anticorps AA545191, anticorps Ddit1, anticorps DDIT1, anticorps Gadd45, anticorps growth arrest and DNA damage inducible alpha L homeolog, anticorps growth arrest and DNA-damage-inducible, alpha, b, anticorps growth arrest and DNA damage inducible alpha, anticorps growth arrest and DNA damage-inducible protein 45, anticorps growth arrest and DNA-damage-inducible 45 alpha, anticorps growth arrest and DNA-damage-inducible, alpha, anticorps gadd45a.L, anticorps gadd45ab, anticorps GADD45A, anticorps gadd45a, anticorps GADD45, anticorps Gadd45a

Sujet: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,DDIT1,GADD45,GADD45A,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,G2/M DNA Damage Checkpoint,Immunology & Inflammation,T Cell Receptor Signaling Pathway,GADD45A

Poids moléculaire: 14 kDa/18 kDa

ID gène: 1647

UniProt: P24522

Pathways: Signalisation p53, Cycle Cellulaire