CFTR anticorps
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- Antigène Voir toutes CFTR Anticorps
- CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CFTR est non-conjugé
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Application
- Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Protein G affinity chromatography
- Immunogène
- Human recombinant protein was used as the immunogen for this CFTR antibody.
- Clone
- CFTR1-1
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CFTR Anticorps primaire
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- Indications d'application
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.
1. Staining of FFPE tissue is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9 for 10-20 min followed by cooling at RT for 20 min.\. Immunofluorescence: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL (1)
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the CFTR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Antigène
- CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
- Autre désignation
- CFTR (CFTR Produits)
- Synonymes
- anticorps ABC35, anticorps ABCC7, anticorps CF, anticorps CFTR/MRP, anticorps MRP7, anticorps TNR-CFTR, anticorps dJ760C5.1, anticorps CFTR, anticorps AW495489, anticorps Abcc7, anticorps RGD1561193, anticorps abc35, anticorps abcc7, anticorps cftr/mrp, anticorps mrp7, anticorps tnr-cftr, anticorps xcftr, anticorps si:dkey-270i2.2, anticorps cystic fibrosis transmembrane conductance regulator, anticorps cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7), anticorps CFTR, anticorps cftr-A, anticorps Cftr, anticorps cftr
- Sujet
- Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
- ID gène
- 1080
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