MAPKAP1 anticorps (C-Term)

N° du produit ABIN3025251

Détail du produit anti-MAPKAP1 anticorps

Antigène: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKAP1 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A purified antibody

Immunogène: A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.\. Western blot: 1-3 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.

Détails sur MAPKAP1

Antigène: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Autre désignation: SIN1 (MAPKAP1 Produits)

Synonymes: anticorps CG10105, anticorps Dmel\\CG10105, anticorps dSin1, anticorps sin1, anticorps MAPKAP1, anticorps im:7143088, anticorps si:ch73-242f23.1, anticorps mip1, anticorps sin1b, anticorps sin1g, anticorps MGC53034, anticorps JC310, anticorps MIP1, anticorps SIN1, anticorps SIN1b, anticorps SIN1g, anticorps AI591529, anticorps D230039K05Rik, anticorps Sin1, anticorps SAPK-interacting protein 1, anticorps mitogen-activated protein kinase associated protein 1, anticorps mitogen-activated protein kinase associated protein 1 L homeolog, anticorps Sin1, anticorps MAPKAP1, anticorps mapkap1, anticorps Mapkap1, anticorps mapkap1.L

Sujet: MTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.

ID gène: 79109

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events