PODXL anticorps (Extracellular Domain)
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- Antigène Voir toutes PODXL Anticorps
- PODXL (Podocalyxin-Like (PODXL))
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Épitope
- Extracellular Domain
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Reactivité
- Humain, Rat, Lapin
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PODXL est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Protein G affinity chromatography
- Immunogène
- A human recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain was used as the immunogen for the Podocalyxin antibody.
- Clone
- 3D3
- Isotype
- IgG1
- Top Product
- Discover our top product PODXL Anticorps primaire
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- Indications d'application
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Podocalyxin antibody to be titered up or down for optimal performance.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Prediluted IHC only format : incubate for 30 min at RT (2) - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, *For IHC use only*
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the Podocalyxin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Antigène
- PODXL (Podocalyxin-Like (PODXL))
- Autre désignation
- Podocalyxin (PODXL Produits)
- Synonymes
- anticorps Gp200, anticorps PC, anticorps PCLP, anticorps PCLP-1, anticorps PCB, anticorps AW121214, anticorps Ly102, anticorps Pclp1, anticorps podocalyxin, anticorps MEP21, anticorps PODXL, anticorps Gp135, anticorps PCLP1, anticorps cPCLP1, anticorps podxl, anticorps fc18d02, anticorps wu:fc18d02, anticorps Pc, anticorps Pcb, anticorps Podxl, anticorps podocalyxin like, anticorps pyruvate carboxylase, anticorps podocalyxin-like, anticorps PODXL, anticorps PC, anticorps Podxl, anticorps podxl, anticorps Pcx
- Sujet
- Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
- ID gène
- 5420
- Pathways
- Tube Formation
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