TGFA anticorps (AA 34-43)

N° du produit ABIN3026446

Détail du produit anti-TGFA anticorps

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Épitope: AA 34-43

Reactivité: Humain, Lapin, Poisson zèbre (Danio rerio)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFA est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Attributs du produit: This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGFa is a growth factor with 33 % homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Purification: Protein G affinity chromatography

Immunogène: Amino acids 34-43 (PPVAAAVVSH) from the human protein were used as the immunogen for this anti-TGF alpha antibody.

Clone: SPM542

Isotype: IgM kappa

Information d'application

Indications d'application: The optimal dilution of the anti-TGF-alpha antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate Buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the anti-TGF-alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur TGFA

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Autre désignation: TGF-alpha (TGFA Produits)

Synonymes: anticorps TFGA, anticorps LOC100009482, anticorps TGF alpha, anticorps TGFA, anticorps wa-1, anticorps wa1, anticorps RATTGFAA, anticorps TGFAA, anticorps NV15606, anticorps si:ch211-10e8.7, anticorps transforming growth factor alpha, anticorps transforming growth factor alpha L homeolog, anticorps transforming growth factor-alpha, anticorps transforming growth factor, alpha, anticorps TGFA, anticorps TGF-A, anticorps Tgfa, anticorps tgfa.L, anticorps LOC100121300, anticorps LOC100009150, anticorps tgfa

Sujet: This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGFa is a growth factor with 33 % homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Pathways: Signalisation NF-kappaB, Signalisation RTK, EGFR Signaling Pathway