UCHL1 anticorps
-
- Antigène Voir toutes UCHL1 Anticorps
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
-
Reactivité
- Humain, Rat, Souris, Boeuf (Vache), Porc
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp UCHL1 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Attributs du produit
- This antibody specifically reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. PGP9.5 antibody has been used to show the protein to be a useful prognostic indicator of colorectal, pancreatic and gall bladder cancer. A mutation in the gene is believed to cause a form of Parkinson's disease.
- Purification
- Protein G affinity chromatography
- Immunogène
- Native protein from brain was used as the immunogen for this PGP9.5 antibody.
- Clone
- 31A3
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product UCHL1 Anticorps primaire
-
-
- Indications d'application
-
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the PGP9.5 antibody to be titered up or down for optimal performance.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. WB: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2) - Restrictions
- For Research Use only
-
- Concentration
- 0.2 mg/mL
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the PGP9.5 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
-
- Antigène
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
- Autre désignation
- PGP9.5 UchL1 (UCHL1 Produits)
- Synonymes
- anticorps PARK5, anticorps PGP 9.5, anticorps PGP9.5, anticorps PGP95, anticorps Uch-L1, anticorps UCH-L1, anticorps UCHL1, anticorps cb358, anticorps wu:fc55h08, anticorps park5, anticorps pgp9.5, anticorps uch-l1, anticorps MGC132191, anticorps uchl1, anticorps AW822034, anticorps C88048, anticorps R75593, anticorps UCHL-1, anticorps gad, anticorps ubiquitin C-terminal hydrolase L1, anticorps ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), anticorps ubiquitin C-terminal hydrolase L1 L homeolog, anticorps ubiquitin carboxyl-terminal esterase L1, anticorps ubiquitin carboxy-terminal hydrolase L1, anticorps UCHL1, anticorps uchl1, anticorps uchl1.L, anticorps LOC100304750, anticorps Uchl1
- Sujet
- This antibody specifically reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. PGP9.5 antibody has been used to show the protein to be a useful prognostic indicator of colorectal, pancreatic and gall bladder cancer. A mutation in the gene is believed to cause a form of Parkinson's disease.
- ID gène
- 7345
- Pathways
- Feeding Behaviour
-