TLR10 anticorps (N-Term)

N° du produit ABIN3029161

Détail du produit anti-TLR10 anticorps

Antigène: TLR10 (Toll-Like Receptor 10 (TLR10))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR10 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminus of human Toll-like receptor 10 (DLKTFEFNKELRYLD) was used as the immunogen for this TLR10 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the TLR10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the TLR10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur TLR10

Antigène: TLR10 (Toll-Like Receptor 10 (TLR10))

Autre désignation: TLR10 (TLR10 Produits)

Synonymes: anticorps TLR10, anticorps CD290, anticorps toll like receptor 10, anticorps toll-like receptor 10, anticorps TLR10, anticorps Tlr10

Sujet: Toll-like receptor 10 is a protein that in humans is encoded by the TLR10 gene. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. By genomic sequence analysis, Hasan et al.(2005) determined that the gene is clustered with TLR1 and TLR6 on chromosome 4p14. By coimmunoprecipitation analysis, Hasan et al.(2005) found that TLR10 associated with itself and with TLR1 and TLR2, but not with MD2. Signaling studies showed that TLR10 required MYD88, but not TIRAP, TRAM(TICAM2), or TRIF (TICAM1), to activate immune system promoters. Pro674 within the TLR10 TIR domain was required to activate all promoter examined.

UniProt: Q9BXR5

Pathways: Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades