ADRA2A anticorps (C-Term)

N° du produit ABIN3029880

Détail du produit anti-ADRA2A anticorps

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human alpha 2a Adrenergic Receptor (FGYCNSSLNPVIYTIFNH) was used as the immunogen for this alpha 2a Adrenergic Receptor antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the alpha 2a Adrenergic Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the alpha 2a Adrenergic Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur ADRA2A

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Autre désignation: alpha 2a Adrenergic Receptor (ADRA2A Produits)

Synonymes: anticorps ADRA2A, anticorps AW122659, anticorps Adra-2, anticorps Adra-2a, anticorps alpha(2A)AR, anticorps alpha2-C10, anticorps alpha2A, anticorps alpha2A-AR, anticorps ADRA2, anticorps ADRA2R, anticorps ADRAR, anticorps ALPHA2AAR, anticorps ZNF32, anticorps CA2-47, anticorps RATRG20, anticorps RG20, anticorps PORA2AR, anticorps adrenoceptor alpha 2A, anticorps alpha-2A adrenergic receptor-like, anticorps adrenergic receptor, alpha 2a, anticorps adra2a, anticorps ADRA2A, anticorps LOC100414445, anticorps Adra2a

Sujet: Alpha-2-adrenergic receptor(ADRA2), also known as platelet type adrenoceptor alpha-2A ,is a member of G protein-coupled receptor superfamily. This gene, which can identify a DraI RFLP of the ADRAR gene, mapped to 10q23-q25, is found in the distal region of mouse chromosome 19 and abundantly expressed in giant cell. ADRA2 acts a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. It has 3 highly homologous subtypes: ADRA2A, ADRA2B and ADRA2C. Studies in mouse suggested that both the ADRA2A and ADRA2C subtypes are required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. ADRA2A receptors inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity