ASIC3 anticorps (N-Term)

N° du produit ABIN3029921

Détail du produit anti-ASIC3 anticorps

Antigène: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASIC3 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminus of human Acid-Sensing Ion Channel 3 (FLYQVAERVRYYREFHHQ) was used as the immunogen for this ASIC3 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the ASIC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the ASIC3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur ASIC3

Antigène: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Autre désignation: ASIC3 (ACCN3 Produits)

Synonymes: anticorps ACCN3, anticorps Accn3, anticorps DRASIC, anticorps SLNAC1, anticorps TNaC1, anticorps AW742291, anticorps TNAC1, anticorps amiloride-sensitive cation channel 3, anticorps acid sensing ion channel subunit 3, anticorps acid-sensing (proton-gated) ion channel 3, anticorps ACCN3, anticorps ASIC3, anticorps Asic3

Sujet: Acid-Sensing Ion Channel 3, also known as Testis sodium channel (TNAC1) or Dorsal root acid-sensing ion channel (DRASIC), is a protein that in humans is encoded by the ASIC3 gene. ASIC3 belongs to a family of acid-sensing channel proteins that are structurally related to epithelial sodium channel proteins and support acid-activated membrane currents. By radiation hybrid analysis, de Weille et al.(1998) mapped the gene to chromosome 7q35. De Weille et al.(1998) found that the human protein supported an H(+)-gated cation current in COS cells with kinetics similar to those of the rat protein. Babinski et al. (1999) expressed homomeric human ASIC3 channels in Xenopus oocytes and found that rapid reduction in extracellular pH resulted in a biphasic response characterized by a fast and rapidly desensitizing current followed by a slow and sustained current that returned to baseline only on return to physiologic pH .

UniProt: Q9UHC3