HSPG2 anticorps (AA 524-701)
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- Antigène Voir toutes HSPG2 Anticorps
- HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
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Épitope
- AA 524-701
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HSPG2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogène
- Human partial recombinant protein (AA 524-701) was used as the immunogen for this Perlecan antibody.
- Isotype
- IgG
- Top Product
- Discover our top product HSPG2 Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the Perlecan antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the Perlecan antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
- Autre désignation
- Perlecan (HSPG2 Produits)
- Synonymes
- anticorps HSPG, anticorps PLC, anticorps PRCAN, anticorps SJA, anticorps SJS, anticorps SJS1, anticorps HSPG2, anticorps AI852380, anticorps Pcn, anticorps Plc, anticorps per, anticorps Per, anticorps heparan sulfate proteoglycan 2, anticorps perlecan (heparan sulfate proteoglycan 2), anticorps HSPG2, anticorps hspg2, anticorps Hspg2
- Sujet
- Perlecan (PLC) also known as HSPG2, is a protein that in humans is encoded by the HSPG2 gene. It is mapped to 1p36.12. Perlecan is highly conserved across species and the available data indicate that it has evolved from ancient ancestors by gene duplication and exonshuffling. It is a key component of the vascular extracellular matrix where it interacts with a variety of other matrix components and helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. Perlecan can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation.
- ID gène
- 3339
- Pathways
- Glycosaminoglycan Metabolic Process, Lipid Metabolism
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