GLUT4 anticorps (AA 333-509)

N° du produit ABIN3032678

Détail du produit anti-GLUT4 anticorps

Antigène: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Épitope: AA 333-509

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLUT4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 333-509) was used as the immunogen for this GLUT4 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the GLUT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the GLUT4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur GLUT4

Antigène: GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))

Autre désignation: GLUT4 (Glucose Transporter 4) (SLC2A4 Produits)

Synonymes: anticorps GLUT4, anticorps Glut-4, anticorps Glut4, anticorps glut4, anticorps slc2a4, anticorps SLC2A4, anticorps solute carrier family 2 member 4, anticorps solute carrier family 2 (facilitated glucose transporter), member 4, anticorps solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog, anticorps SLC2A4, anticorps Slc2a4, anticorps GLUT4, anticorps slc2a4.L

Sujet: Glucose transporter 4, also known as SLC2A4 or Solute carrier family 2 (facilitated glucose transporter) member 4, is a protein that in humans is encoded by the GLUT4 gene. It is mapped to 17p13.1. This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

ID gène: 6517

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, L'effet Warburg