Midkine anticorps (AA 21-143)

N° du produit ABIN3042356

Détail du produit anti-Midkine anticorps

Antigène: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Épitope: AA 21-143

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Midkine est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Midkine(MDK) detection. Tested with WB in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Midkine(MDK) detection. Tested with WB in Human.
Gene Name: midkine (neurite growth-promoting factor 2)
Protein Name: Midkine

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Midkine recombinant protein (Position: V21-D143). Human Midkine shares 87% and 89% amino acid (aa) sequence identity with mouse and rat Midkine, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Midkine is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur Midkine

Antigène: Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))

Autre désignation: MDK (MDK Produits)

Synonymes: anticorps ARAP, anticorps MK, anticorps NEGF2, anticorps Mek, anticorps MK-B, anticorps PTF-alpha-1, anticorps mdk, anticorps midkine, anticorps negf2, anticorps RIHB, anticorps cb518, anticorps fb79b05, anticorps fj33b02, anticorps fj48a12, anticorps mdk2, anticorps plei2, anticorps wu:fb79b05, anticorps wu:fj33b02, anticorps wu:fj48a12, anticorps MK-A, anticorps PTF-alpha-2, anticorps X-PTF-alpha1, anticorps XMK, anticorps mdk-a, anticorps mdk-b, anticorps midkine, anticorps midkine L homeolog, anticorps midkine (neurite growth-promoting factor 2), anticorps midkine b, anticorps midkine S homeolog, anticorps MDK, anticorps Mdk, anticorps mdk.L, anticorps mdkb, anticorps mdk.S

Sujet: Midkine(MK or MDK), also known as neurite growth-promoting factor 2(NEGF2), is a protein that in humans is encoded by the MDK gene. Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin(NEGF1, 46 % homologous with MK). It is a nonglycosylated protein, composed of two domains held by disulfide bridges. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair. Midkine is pleiotropic, capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis. A molecular complex containing receptor-type tyrosine phosphatase zeta(PTPζ), low density lipoprotein receptor-related protein(LRP1), anaplastic leukemia kinase (ALK) and syndecans is considered to be its receptor.

Synonyms: Amphiregulin associated protein antibody|Amphiregulin-associated protein antibody|ARAP antibody|FLJ27379 antibody|MDK antibody|Midgestation and kidney protein antibody|Midkine antibody|MK 1 antibody|MK antibody|MK_HUMAN antibody|MK1 antibody|NEGF 2 antibody|NEGF2 antibody|neurite growth promoting factor 2 antibody|Neurite outgrowth promoting protein antibody|Neurite outgrowth-promoting factor 2 antibody|Neurite outgrowth-promoting protein antibody|Retinoic acid inducible factor antibody

ID gène: 4192

UniProt: P21741

Pathways: Signalisation RTK, M Phase, Skeletal Muscle Fiber Development