GRIN2C anticorps (AA 43-242)

N° du produit ABIN3042433

Détail du produit anti-GRIN2C anticorps

Antigène: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Épitope: AA 43-242

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIN2C est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, NMDA 2C(GRIN2C) detection. Tested with WB in Human,Rat.

Réactivité croisée (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, NMDA 2C(GRIN2C) detection. Tested with WB in Human,Rat.
Gene Name: glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Protein Name: Glutamate receptor ionotropic, NMDA 2C

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NMDAR2C recombinant protein (Position: Q43-Q242). Human NMDAR2C shares 93% and 92.5% amino acid (aa) sequence identity with mouse and rat NMDAR2C, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for NMDAR2C is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur GRIN2C

Antigène: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Autre désignation: GRIN2C (GRIN2C Produits)

Synonymes: anticorps GRIN2C, anticorps NMDAR2C, anticorps il12rb2l, anticorps il-12rb2.b, anticorps nr2c, anticorps GluN2C, anticorps NR2C, anticorps glutamate ionotropic receptor NMDA type subunit 2C, anticorps interleukin 12 receptor, beta 2a, like, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2C S homeolog, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2C, anticorps glutamate receptor, ionotropic, NMDA2C (epsilon 3), anticorps GRIN2C, anticorps il12rb2l, anticorps grin2c.S, anticorps grin2c, anticorps Grin2c

Sujet: NMDAR2C, known as GRIN2C, is mapped to 17q25.1. Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.

Synonyms: GluN2C antibody|Glutamate [NMDA] receptor subunit epsilon-3 antibody|Glutamate Receptor Ionotropic N Methyl D Aspartate 2C antibody|Glutamate receptor ionotropic, NMDA 2C antibody|Glutamate receptor, ionotropic, N methyl D aspartate 2C antibody|Grin2c antibody|N Methly D Aspartate Receptor Channel Subunit Epsilon 3 antibody|N Methyl D Aspartate Receptor Subtype 2C antibody|N methyl D aspartate receptor subunit 2C antibody|N-methyl D-aspartate receptor subtype 2C antibody|NMDAR2C antibody|NMDE3_HUMAN antibody|NR2C antibody|OTTHUMP00000041930 antibody

ID gène: 2905

UniProt: Q14957

Pathways: Synaptic Membrane