RAP1A anticorps (C-Term)

N° du produit ABIN3042496

Détail du produit anti-RAP1A anticorps

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Épitope: AA 156-181, C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAP1A est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Ras-related protein Rap-1A(RAP1A) detection. Tested with WB in Human,Rat.

Séquence: EIFYDLVRQI NRKTPVEKKK PKKKSC

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Ras-related protein Rap-1A(RAP1A) detection. Tested with WB in Human,Rat.
Gene Name: RAP1A, member of RAS oncogene family
Protein Name: Ras-related protein Rap-1A

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human RAP1A (156-181aa EIFYDLVRQINRKTPVEKKKPKKKSC), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur RAP1A

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Autre désignation: RAP1A (RAP1A Produits)

Synonymes: anticorps KREV-1, anticorps KREV1, anticorps RAP1, anticorps SMGP21, anticorps AI848598, anticorps G-22K, anticorps Krev-1, anticorps Rap1, anticorps RAP-1A, anticorps rap 1A, anticorps wu:fc66g06, anticorps zgc:86676, anticorps krev-1, anticorps krev1, anticorps rap1, anticorps RAP1A, member of RAS oncogene family, anticorps RAS-related protein 1a, anticorps RAP1A, member of RAS oncogene family a, anticorps RAP1A, member of RAS oncogene family L homeolog, anticorps RAP1A, anticorps Rap1a, anticorps rap1aa, anticorps rap1a.L

Sujet: Ras-related protein Rap-1A is a protein that in humans is encoded by the RAP1A gene. This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. And it is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. Additionally, the encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Synonyms: C21KG antibody|G 22K antibody|G-22K antibody|GTP binding protein smg p21A antibody|GTP-binding protein smg p21A antibody|KREV 1 antibody|KREV1 antibody|OTTHUMP00000013741 antibody|RAP 1A antibody|RAP1 antibody|RAP1A antibody|RAP1A member of RAS oncogene family antibody|RAP1A_HUMAN antibody|Ras related protein Krev 1 antibody|Ras related protein Rap 1A antibody|RAS related protein RAP1A antibody|Ras-related protein Krev-1 antibody|Ras-related protein Rap-1A antibody|SMGP21 antibody

ID gène: 5906

UniProt: P62834

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor