P2RX7 anticorps (N-Term)

N° du produit ABIN3042888

Détail du produit anti-P2RX7 anticorps

Antigène: P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))

Épitope: AA 1-20, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P2RX7 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for P2X purinoceptor 7(P2RX7) detection. Tested with WB in Human,Mouse,Rat.

Séquence: MPACCSWNDV FQYETNKVTR

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for P2X purinoceptor 7(P2RX7) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: purinergic receptor P2X, ligand-gated ion channel, 7
Protein Name: P2X purinoceptor 7

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of rat P2RX7(1-20aa MPACCSWNDVFQYETNKVTR), different from the related mouse sequence by one amino acid, and from the related human sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur P2RX7

Antigène: P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))

Autre désignation: P2RX7 (P2RX7 Produits)

Synonymes: anticorps p2xr7, anticorps P2RX7, anticorps P2X7, anticorps AI467586, anticorps P2X(7), anticorps P2X7R, anticorps p2x7, anticorps purinergic receptor P2X 7, anticorps purinergic receptor P2X, ligand-gated ion channel, 7, anticorps P2X purinoceptor 7, anticorps P2RX7, anticorps p2rx7, anticorps LOC100458463, anticorps P2rx7

Sujet: P2X purinoceptor 7, also called P2X7, is a protein that in humans is encoded by the P2RX7 gene. The product of this gene belongs to the family of purnoceptors for ATP. P2RX7 was mapped to chromosome 12q24 by fluorescence in situ hybridization. It is a receptor for ATP that acts as a ligand-gated ion channel. This gene is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. It could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.

Synonyms: ATP receptor antibody|P2X purinoceptor 7 antibody|P2X7 antibody|P2Z receptor antibody|Purinergic receptor antibody|purinergic receptor P2X, ligand gated ion channel, 7 antibody

UniProt: Q64663

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis