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IL-6 anticorps (C-Term)

IL6 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3043090
  • Antigène Voir toutes IL-6 (IL6) Anticorps
    IL-6 (IL6) (Interleukin 6 (IL6))
    Épitope
    • 19
    • 17
    • 15
    • 15
    • 15
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 195-212, C-Term
    Reactivité
    • 181
    • 135
    • 73
    • 28
    • 22
    • 21
    • 15
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    Humain
    Hôte
    • 194
    • 84
    • 72
    • 13
    • 4
    • 3
    • 2
    Lapin
    Clonalité
    • 214
    • 155
    • 1
    Polyclonal
    Conjugué
    • 199
    • 63
    • 27
    • 12
    • 11
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-6 est non-conjugé
    Application
    • 266
    • 139
    • 105
    • 62
    • 52
    • 50
    • 41
    • 41
    • 38
    • 31
    • 25
    • 25
    • 22
    • 20
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    Rabbit IgG polyclonal antibody for Interleukin-6(IL6) detection. Tested with WB in Human.
    Séquence
    LRSFKEFLQS SLRALRQM
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Interleukin-6(IL6) detection. Tested with WB in Human.
    Gene Name: interleukin 6(interferon, beta 2)
    Protein Name: Interleukin-6(IL-6)
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of human IL-6(195-212aa LRSFKEFLQSSLRALRQM).
    Isotype
    IgG
    Top Product
    Discover our top product IL6 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Wu, Li, Cui, Wu, Hong, Li, Wu, Jie, Wang, Li: "The Natural Flavone Acacetin Confers Cardiomyocyte Protection Against Hypoxia/Reoxygenation Injury via AMPK-Mediated Activation of Nrf2 Signaling Pathway." dans: Frontiers in pharmacology, Vol. 9, pp. 497, (2018) (PubMed).

    Lu, Kang, Hu, Tang, Zhou, Yu, Li, Xu: "Angiotensin-(1-7) inhibits inflammation and oxidative stress to relieve lung injury induced by chronic intermittent hypoxia in rats." dans: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 49, Issue 10, pp. e5431, (2017) (PubMed).

    Chen, Zhao, Zhang, Yang, Zhao, Zhang, Yan, Pan, Li, Zhang, Li: "Tangshen Formula Attenuates Colonic Structure Remodeling in Type 2 Diabetic Rats." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 4064156, (2017) (PubMed).

    Li, Lu, Sun, Zuo, Wang, Yan: "Inhibition of endoplasmic reticulum stress signaling pathway: A new mechanism of statins to suppress the development of abdominal aortic aneurysm." dans: PLoS ONE, Vol. 12, Issue 4, pp. e0174821, (2017) (PubMed).

    Chen, Wang, Li, Jiang, Lu, Zhou: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." dans: Journal of diabetes research, Vol. 2016, pp. 9726503, (2016) (PubMed).

    Wang, Qiu, Ren: "Inhibition of acute lung injury by rubriflordilactone in LPS-induced rat model through suppression of inflammatory factor expression." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 12, pp. 15954-9, (2016) (PubMed).

    Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: "A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes." dans: Natural products and bioprospecting, Vol. 5, Issue 3, pp. 159-66, (2015) (PubMed).

    Chen, Zhao, Wu, Zou, Luo, Li, Xie, Liang: "The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 12, pp. 8411-20, (2015) (PubMed).

    Hu, Jing, Wang, Zhang, Yong, Wang: "The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D-Galactose-induced aged rat model." dans: BMC complementary and alternative medicine, Vol. 15, pp. 119, (2015) (PubMed).

    Li, Zhang, Fu, Sun, Gong, Jiang, Zhang: "Dual pancreas- and lung-targeting therapy for local and systemic complications of acute pancreatitis mediated by a phenolic propanediamine moiety." dans: Journal of controlled release : official journal of the Controlled Release Society, Vol. 212, pp. 19-29, (2015) (PubMed).

    Cui, Feng, Zhang, Jia: "The anti-inflammation effect of baicalin on experimental colitis through inhibiting TLR4/NF-?B pathway activation." dans: International immunopharmacology, Vol. 23, Issue 1, pp. 294-303, (2015) (PubMed).

    Li, Chen, Zhang, Song, Mu: "Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model rats." dans: Neural regeneration research, Vol. 7, Issue 5, pp. 325-31, (2015) (PubMed).

    Gong, Wang, Yuan, Li, Gu, Zhao, Zhang, Jia, Feng, Liu: "Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 630760, (2015) (PubMed).

    Li, Zhang, Jiang, Yin, Fan, Sun, Chen, Li, Liu: "Protective effects of thalidomide on pulmonary injuries in a rat model of paraquat intoxication." dans: Journal of inflammation (London, England), Vol. 12, pp. 46, (2015) (PubMed).

    Li, Qian, Ju, Wang: "Upregulation of Toll-like receptor 2 expression in colorectal cancer infected by human cytomegalovirus." dans: Oncology letters, Vol. 9, Issue 1, pp. 365-370, (2014) (PubMed).

    Liu, Zeng, Liu, Wang, Maitz, Wang, Liu, Chen, Huang: "Surface modification with dopamine and heparin/poly-L-lysine nanoparticles provides a favorable release behavior for the healing of vascular stent lesions." dans: ACS applied materials & interfaces, Vol. 6, Issue 11, pp. 8729-43, (2014) (PubMed).

    Zhu, Mu, Zeng, Xu, Liu, Zhang, Li, Chen, Li, Wang: "Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging." dans: PLoS ONE, Vol. 9, Issue 6, pp. e101291, (2014) (PubMed).

    Huang, Du, Fan, Lv, Qian, Zhang, Han, Chen, Wu, Jin: "The effect of proinflammatory cytokines on IL-17RA expression in NSCLC." dans: Medical oncology (Northwood, London, England), Vol. 31, Issue 9, pp. 144, (2014) (PubMed).

    Ye, Zheng, Fan, Qin, Li, Tang, Ai, Zhang, Bian, Dang, Huang, Zhou, Zhou, Xiong, Yan, Ma, Li: "Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice." dans: PLoS ONE, Vol. 9, Issue 7, pp. e103298, (2014) (PubMed).

    Wang, Zhou, Chen, Zhu: "Putative role of ischemic postconditioning in a rat model of limb ischemia and reperfusion: involvement of hypoxia-inducible factor-1? expression." dans: Brazilian journal of medical and biological research = Revista brasileira de pesquisas me?dicas e biolo?gicas / Sociedade Brasileira de Biofi?sica ... [et al.], Vol. 47, Issue 9, pp. 738-45, (2014) (PubMed).

  • Antigène
    IL-6 (IL6) (Interleukin 6 (IL6))
    Autre désignation
    IL6 (IL6 Produits)
    Synonymes
    anticorps BSF2, anticorps HGF, anticorps HSF, anticorps IFNB2, anticorps IL-6, anticorps Il-6, anticorps ILg6, anticorps Ifnb2, anticorps il6, anticorps CHIL-6, anticorps interleukin 6, anticorps interleukin-6, anticorps IL6, anticorps Il6, anticorps il-6, anticorps IL-6
    Sujet
    Interleukin-6(IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is one of the most important mediators of fever and of the acute phase response. IL-6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Bowcock et al.(1988) assigned the IL6 gene to chromosome 7p21. By in situ hybridization and Southern blot analysis of mouse-human hybrid cell lines, Sutherland et al.(1988) mapped the IL6 gene to chromosome 7p15.

    Synonyms: Interleukin BSF 2 antibody|B cell differentiation factor antibody|B cell stimulatory factor 2 antibodyB-cell stimulatory factor 2 antibody|BSF 2 antibody|BSF-2 antibody|BSF2 antibody|CDF antibody|CTL differentiation factor antibody|Cytotoxic T cell differentiation factor antibody|Hepatocyte stimulating factor antibody|HGF antibody|HPGF antibody|HSF antibody|Hybridoma growth factor antibody|Hybridoma growth factor Interferon beta-2 antibody|Hybridoma plasmacytoma growth factor antibody|IFN-beta-2 antibody|IFNB2 antibody|IL 6 antibody|IL-6 antibody|IL6 antibody|IL6 protein antibody|IL6_HUMAN antibody|Interferon beta 2 antibody|Interferon beta-2 antibody|Interleukin 6(interferon beta 2) antibody|Interleukin 6 antibody|Interleukin-6 antibody|Interleukin6 antibody
    UniProt
    P05231
    Pathways
    Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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