FAK anticorps (C-Term)
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- Antigène Voir toutes FAK (PTK2) Anticorps
- FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
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Épitope
- AA 1036-1052, C-Term
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FAK est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit IgG polyclonal antibody for Focal adhesion kinase 1(PTK2) detection. Tested with WB in Human,Mouse,Rat.
- Séquence
- DVIDQARLKM LGQTRPH
- Réactivité croisée (Details)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Attributs du produit
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Rabbit IgG polyclonal antibody for Focal adhesion kinase 1(PTK2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: PTK2 protein tyrosine kinase 2
Protein Name: Focal adhesion kinase 1(FADK 1) - Purification
- Immunogen affinity purified.
- Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human FAK(1036-1052aa DVIDQARLKMLGQTRPH), identical to the related rat and mouse sequences.
- Isotype
- IgG
- Top Product
- Discover our top product PTK2 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Agent conservateur
- Thimerosal (Merthiolate), Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Date de péremption
- 12 months
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Research of shRNAmir inhibitory effects towards focal adhesion kinase expression in the treatment of gastric cancer." dans: Oncology letters, Vol. 9, Issue 2, pp. 595-603, (2015) (PubMed).
: "Correlation between matrix metalloproteinase expression and activation of the focal adhesion kinase signaling pathway in herpes stromal keratitis." dans: Experimental and therapeutic medicine, Vol. 7, Issue 1, pp. 280-286, (2013) (PubMed).
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Research of shRNAmir inhibitory effects towards focal adhesion kinase expression in the treatment of gastric cancer." dans: Oncology letters, Vol. 9, Issue 2, pp. 595-603, (2015) (PubMed).
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- Antigène
- FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
- Autre désignation
- PTK2 (PTK2 Produits)
- Synonymes
- anticorps FADK, anticorps FAK, anticorps FAK1, anticorps FRNK, anticorps PPP1R71, anticorps p125FAK, anticorps pp125FAK, anticorps PTK2, anticorps Fadk, anticorps mKIAA4203, anticorps fak, anticorps fak1a, anticorps ptk2, anticorps ptk2a, anticorps wu:fa18c04, anticorps zgc:66114, anticorps CG10023, anticorps CT28129, anticorps DFAK, anticorps DFak, anticorps DFak56, anticorps Dfak, anticorps Dfak56, anticorps DmFAK, anticorps Dmel\\CG10023, anticorps Fak56, anticorps Fak56D, anticorps fak56, anticorps protein tyrosine kinase 2, anticorps protein tyrosine kinase 2 L homeolog, anticorps PTK2 protein tyrosine kinase 2, anticorps protein tyrosine kinase 2ab, anticorps Focal adhesion kinase, anticorps PTK2, anticorps ptk2.L, anticorps Ptk2, anticorps ptk2ab, anticorps Fak
- Sujet
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PTK2 protein tyrosine kinase 2 (PTK2), also known as Focal Adhesion Kinase (FAK), is a protein that, in humans, is encoded by the PTK2 gene. This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Synonyms: FADK 1 antibody|FADK antibody|FAK 1 antibody|FAK related non kinase polypeptide antibody|FAK1 antibody|FAK1_HUMAN antibody|Focal adhesion kinase 1 antibody|Focal adhesion kinase related nonkinase antibody|FRNK antibody|p125FAK antibody|pp125FAK antibody|PPP1R71 antibody|Protein phosphatase 1 regulatory subunit 71 antibody|Protein tyrosine kinase 2 antibody|Protein Tyrosine Kinase Cytoplasmic antibody|Protein-tyrosine kinase 2 antibody|PTK 2 antibody|PTK2 antibody|PTK2 protein tyrosine kinase 2 antibody - UniProt
- Q05397
- Pathways
- Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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