SGK1 anticorps (N-Term)

N° du produit ABIN3043433

Détail du produit anti-SGK1 anticorps

Antigène: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Épitope: AA 28-55, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGK1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase Sgk1(SGK1) detection. Tested with WB in Human.

Séquence: MKQRRMGLND FIQKIANNSY ACKHPEVQ

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase Sgk1(SGK1) detection. Tested with WB in Human.
Gene Name: serum/glucocorticoid regulated kinase 1
Protein Name: Serine/threonine-protein kinase Sgk1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human SGK1 (28-55aa MKQRRMGLNDFIQKIANNSYACKHPEVQ), different from the related mouse sequence by three amino acids, and from the related rat sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SGK1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-SGK1 (ABIN3043433)

Chang, Bok, Sun, Edwards, Huang: "Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress." dans: PLoS genetics, Vol. 12, Issue 10, pp. e1006356, (2017) (PubMed).

Détails sur SGK1

Antigène: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Autre désignation: SGK1 (SGK1 Produits)

Synonymes: anticorps SGK, anticorps Sgk, anticorps sgk-B, anticorps sgk2, anticorps cb1083, anticorps sgk, anticorps wu:fc20a09, anticorps sgk-A, anticorps sgk1, anticorps sgk1-a, anticorps sgk1-b, anticorps serum/glucocorticoid regulated kinase 1, anticorps Serine/threonine-protein kinase sgk-1, anticorps serum/glucocorticoid regulated kinase 1 S homeolog, anticorps serum/glucocorticoid regulated kinase 1 L homeolog, anticorps SGK1, anticorps Sgk1, anticorps sgk-1, anticorps sgk1.S, anticorps sgk1, anticorps sgk1.L

Sujet: Serine/threonine-protein kinase Sgk1, also called SGK1, encodes a serine/threonine protein kinase that plays an important role in cellular stress response. By fluorescence in situ hybridization, this gene is mapped to 6q23.2. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Synonyms: Serine/threonine protein kinase SGK antibody|Serine/threonine protein kinase Sgk1 antibody| Serine/threonine-protein kinase Sgk1 antibody|Serum and glucocorticoid regulated kinase antibody|Serum/glucocorticoid regulated kinase 1 antibody|Serum/glucocorticoid regulated kinase antibody|Serum/glucocorticoid-regulated kinase 1 antibody|SGK 1 antibody|SGK antibody|SGK1 antibody|SGK1_HUMAN antibody

ID gène: 6446

UniProt: O00141

Pathways: Signalisation MAPK, Signalisation Notch, Steroid Hormone Mediated Signaling Pathway