GJB2 anticorps (N-Term)

N° du produit ABIN3043684

Détail du produit anti-GJB2 anticorps

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Épitope: AA 1-16, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GJB2 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Gap junction beta-2 protein(GJB2) detection. Tested with WB in Human,Mouse,Rat.

Séquence: MDWGTLQTIL GGVNKH

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Gap junction beta-2 protein(GJB2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: gap junction protein, beta 2, 26 kDa
Protein Name: Gap junction beta-2 protein

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human GJB2(1-16aa, MDWGTLQTILGGVNKH), different from the related mouse and rat sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur GJB2

Antigène: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Autre désignation: GJB2 (GJB2 Produits)

Synonymes: anticorps ppk, anticorps cx26, anticorps dfna3, anticorps dfnb1, anticorps nsrd1, anticorps dfna3a, anticorps dfnb1a, anticorps MGC53062, anticorps connexin-26, anticorps GJB2, anticorps AI325222, anticorps Cnx26, anticorps Cx26, anticorps Gjb-2, anticorps CXN-26, anticorps CX26, anticorps DFNA3, anticorps DFNA3A, anticorps DFNB1, anticorps DFNB1A, anticorps HID, anticorps KID, anticorps NSRD1, anticorps PPK, anticorps gap junction protein beta 2 L homeolog, anticorps gap junction protein beta 2, anticorps gap junction protein, beta 2, anticorps gjb2.L, anticorps GJB2, anticorps Gjb2

Sujet: Connexin26(CX26), also known as GAP junction protein, beta2, GJB2. Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The 3-prime untranslated region of the CX26 transcript contains a putative mRNA instability sequence. The deduced 226-amino acid protein has a calculated molecular mass of about 26 kD. CX26 shares 92.5 % identity with rat Cx26. connexin 26(GJB2) is assigned to human chromosome 13q11-q12 .Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. Connexin 26 gene(GJB2) mutation modulates the severity of hearing loss associated with the 1555A-G mitochondrial mutation.

Synonyms: connexin 26 antibody|Connexin-26 antibody|cx26 antibody|CXB2_HUMAN antibody|DFNA3 antibody|DFNB1 antibody|Gap junction beta-2 protein antibody|GJB2 antibody|HID antibody|KID antibody|NSRD1 antibody|PPK antibody

UniProt: P29033

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization