ARG2 anticorps (N-Term)

N° du produit ABIN3044188

Détail du produit anti-ARG2 anticorps

Antigène: ARG2 (Arginase, Type II (ARG2))

Épitope: AA 67-85, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARG2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Arginase-2, mitochondrial(ARG2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: DFGDLSFTPV PKDDLYNNL

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Arginase-2, mitochondrial(ARG2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: arginase, type II
Protein Name: Arginase-2, mitochondrial

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Arg2(67-85aa DFGDLSFTPVPKDDLYNNL), different from the related mouse sequence by three amino acids and from the related rat sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ARG2

Antigène: ARG2 (Arginase, Type II (ARG2))

Autre désignation: ARG2 (ARG2 Produits)

Synonymes: anticorps AII, anticorps AU022422, anticorps zgc:65793, anticorps zgc:85630, anticorps wu:fb67g02, anticorps ARG2, anticorps LeARG2, anticorps arg1, anticorps arg3, anticorps arg2, anticorps arg2-c, anticorps arg2-b, anticorps arginase 2, anticorps arginase type II, anticorps arginase 2 L homeolog, anticorps arginase 2 S homeolog, anticorps ARG2, anticorps Arg2, anticorps arg2, anticorps arg2.L, anticorps arg2.S

Sujet: ARG2(arginase, type II) encodes a 355-amino acid polypeptide. Using Northern blotting and RT-PCR, Vockley et al.(1996) found that ARG2 is expressed as a 1.5-kb mRNA in a wide variety of tissues, with highest levels of expression in prostate, brain, and kidney. By PCR analysis of somatic cell hybrid panels, fluorescence in situ hybridization, and radiation hybrid analysis, the ARG2 gene is mapped to 14q24.1-q24.3. ARG2 may be inducible and may be essential in the regulation of nitric oxide synthesis by modulating local arginine concentrations. Gotoh et al.(1996) showed that ARG2 mRNA and nitric oxide synthase(NOS) mRNA were coinduced by lipopolysaccharide in a macrophage-like cell line. Arginase II has been implicated in the regulation of the arginine/ornithine concentrations in the cell. The mitochondrial location of ARG2 and its coinduction with ornithine aminotransferase and involvement with proline biosynthesis in lactating rat mammary gland had led to the inference that ARG2 is involved in biosynthetic functions, as opposed to the metabolic ones of the urea cycle.

Synonyms: ARG2 antibody|ARGI2_HUMAN antibody|Arginase II mitochondrial antibody|Arginase type II antibody|Arginase-2 antibody|arginase-2, mitochondrial antibody|Kidney arginase antibody|Kidney type arginase antibody|Kidney-type arginase antibody|L arginine amidinohydrolase antibody|L arginine ureahydrolase antibody|mitochondrial antibody|Non hepatic arginase antibody|Non-hepatic arginase antibody|Nonhepatic arginase antibody|Type II arginase antibody

UniProt: P78540