Tyrosine Hydroxylase anticorps

N° du produit ABIN308677

Détail du produit anti-Tyrosine Hydroxylase anticorps

Antigène: Tyrosine Hydroxylase (TH)

Reactivité: Humain, Rat, Souris, Protozoa

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp Tyrosine Hydroxylase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Réactivité croisée: Humain, Souris, Primate, Rat (Rattus)

Purification: affinity purified

Immunogène: Native rat tyrosine hydroxylase purified from pheochromocytoma.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Détails sur Tyrosine Hydroxylase

Antigène: Tyrosine Hydroxylase (TH)

Autre désignation: Tyrosine Hydroxylase (TH Produits)

Synonymes: anticorps DYT14, anticorps DYT5b, anticorps TYH, anticorps The, anticorps CG10118, anticorps DH65B, anticorps DTH, anticorps Dmel\\CG10118, anticorps Pale, anticorps Ple, anticorps TH, anticorps Th, anticorps VII, anticorps dTH1, anticorps dTH65B, anticorps pale/ple, anticorps th, anticorps dyt14, anticorps dyt5b, anticorps tyh, anticorps tyrosine hydroxylase, anticorps pale, anticorps tyrosine 3-monooxygenase, anticorps tyrosine hydroxylase S homeolog, anticorps TH, anticorps Th, anticorps ple, anticorps th, anticorps th.S, anticorps LOC100008895

Sujet: Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine, epinephrine and norepinephrine. Therefore the regulation of the TH enzyme represents the central means for controlling the synthesis of these important catecholamines. TH has a large molecular diversity, resulting from differential splicing of its mRNA, which is tissue specific and might result in long term changes in activity of the enzyme and the availability of neurotransmitter at various synapses. The presence of different DNA sequences at the TH locus confers susceptibility to various disorders of the brain including manic-depression and schizophrenia. Parkinson's disease is also considered a TH deficiency, as low dopamine levels are a consistent neurochemical abnormality.

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour