IL-6 anticorps

N° du produit ABIN317142

Cet anticorps anti-IL-6 Monoclonal Rat (Clone 6B4 IGH 54) (ABIN317142) détecte spécifiquement IL-6 dans EIA et Func. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour IL-6 anticorps (ABIN317142)

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-6 est non-conjugé

Application: Enzyme Immunoassay (EIA), Functional Studies (Func)

Clone: 6B4 IGH 54

Détail du produit anti-IL-6 anticorps

Attributs du produit: Synonyms: IL-6, Interferon beta-2, IFNB2, B-cell stimulatory factor 2, BSF-2, CDF, Hybridoma growthfactor, CTL differentiation factor

Purification: Purified IgG prepared by affinity chromatography on protein G

Immunogène: Natural partially purified mouse IL-6.

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Functional Assays: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0mg/mL

Buffer: Phosphate buffered saline

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IL-6

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Autre désignation: Interleukin-6 (IL6)

Sujet: IL-6 is a multifunctional pro-inflammatory cytokine secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts, which acts as the principle inducer of the acute phase response in the liver. IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130), but can also stimulate cells expressing gp130 through a soluble IL-6R. IL-6 has been shown to stimulate B cell differentiation and subsequent immunoglobulin production, promote hybridoma growth, as well as regulating bone metabolism and stimulating energy mobilisation in muscle and fatty tissue.Synonyms: B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFNB2, IL-6, Interferon beta-2

UniProt: P08505

Pathways: Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome