HRK anticorps (Middle Region)
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- Antigène Voir toutes HRK Anticorps
- HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HRK est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects Harakiri (HRK), also known as DP5.
- Purification
- Purified
- Immunogène
- 15 amino acid peptide from near the centre of human HRK (NP_003797).
- Isotype
- IgG
- Top Product
- Discover our top product HRK Anticorps primaire
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- Indications d'application
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Western Blot: 2 - 5g/mL, detects a band of approximately 13 kDa in mouse pancreas tissuelysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
- Autre désignation
- Harakiri / HRK (HRK Produits)
- Synonymes
- anticorps DP5, anticorps HARAKIRI, anticorps AI838259, anticorps Bid3, anticorps harakiri, anticorps Dp5, anticorps harakiri, BCL2 interacting protein, anticorps harakiri, BCL2 interacting protein (contains only BH3 domain), anticorps HRK, anticorps Hrk
- Sujet
- HRK is a BH3 only protein of the Bcl-2 family, which promotes Bax dependent apoptosis. HRK regulates apoptosis through its interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL, and in conjunction to the mitochondrial pore forming protein p32. HRK is thought to have a specific role in initiating neuronal and haematopoietic cell apoptosis, in particular to growth factor deprivation. Aberrant methylation of HRK is frequently detected in primary colorectal cancers. Despite its predicted molecular weight, HRK often migrates at 12-15kD.Synonyms: Activator of apoptosis harakiri, BH3-interacting domain-containing protein 3, BID3, Neuronal death protein DP5
- ID gène
- 8739
- NCBI Accession
- NP_003797
- UniProt
- O00198
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