PIN1 anticorps (N-Term)
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- Antigène Voir toutes PIN1 Anticorps
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
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Épitope
- AA 1-163, N-Term
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PIN1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Purification
- Protein-G affinity chromatography
- Immunogène
- Recombinant human Pin1 (1-163 aa) purified from E. coli
- Clone
- 3G8
- Isotype
- IgG1
- Top Product
- Discover our top product PIN1 Anticorps primaire
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- Indications d'application
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ELISA. Western blot: 1/500-1/1,000, recommended starting dilution 1/500).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4 with 0.09 % Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. - Date de péremption
- 12 months
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- Antigène
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
- Autre désignation
- PIN1 (PIN1 Produits)
- Synonymes
- anticorps DOD, anticorps UBL5, anticorps dod, anticorps ubl5, anticorps pin1, anticorps pin1a, anticorps 0610025L01Rik, anticorps D9Bwg1161e, anticorps pin1b, anticorps zgc:73206, anticorps PPIase pin1, anticorps MdPin1, anticorps Pin1, anticorps peptidylprolyl cis/trans isomerase, NIMA-interacting 1, anticorps peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog, anticorps protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1, anticorps peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog, anticorps peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, anticorps peptidyl-prolyl cis-trans isomerase Pin1, anticorps PIN1, anticorps Pin1, anticorps pin1, anticorps pin1.S, anticorps pin1.L, anticorps ppiD, anticorps PITG_11123, anticorps LOC103419188
- Sujet
- Human Pin1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation. Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA ,PLK I, Wee, and Myt1 kinases), several transcription factors like beta-Catenin, c-Jun, and the tumor suppressor protein p53 , and some specific proteins like the RNA Pol II, the cytoskeleton protein tau, and the G1/S protein Cyclin D1.Synonyms: PIN-1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1
- UniProt
- Q13526
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