KCNJ3 anticorps (Cytoplasmic Domain)

N° du produit ABIN350396

Détail du produit anti-KCNJ3 anticorps

Antigène: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Épitope: Cytoplasmic Domain

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNJ3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for KCNJ3.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from the cytoplasmic domain of human KCNJ3 (GIRK1, Kir3.1) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Isotype: IgG

Information d'application

Indications d'application: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur KCNJ3

Antigène: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Autre désignation: KCNJ3 (KCNJ3 Produits)

Synonymes: anticorps GIRK1, anticorps KGA, anticorps KIR3.1, anticorps Kcnf3, anticorps Kir3.1, anticorps girk1, anticorps potassium voltage-gated channel subfamily J member 3, anticorps potassium inwardly-rectifying channel, subfamily J, member 3, anticorps KCNJ3, anticorps Kcnj3

Sujet: FUNCTION: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. Subcellular location: Membrane, Multi-pass membrane protein.,Inward Rectifier,G protein-activated inward rectifier potassium channel 1, GIRK1, Potassium channel, inwardly rectifying subfamily J member 3, Inward rectifier K(+) channel Kir3.1

UniProt: P48549