CBX4 anticorps (C-Term)
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- Antigène Voir toutes CBX4 Anticorps
- CBX4 (Chromobox Homolog 4 (CBX4))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CBX4 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody is specific to CBX4 (C-term).
- Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CBX4.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product CBX4 Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- CBX4 (Chromobox Homolog 4 (CBX4))
- Autre désignation
- CBX4 / PC2 (CBX4 Produits)
- Synonymes
- anticorps MPc2, anticorps PC2, anticorps NBP16, anticorps XPolycomb, anticorps cbx4-a, anticorps im:6911625, anticorps zgc:158588, anticorps chromobox 4, anticorps chromobox 4 S homeolog, anticorps chromobox homolog 4, anticorps chromobox homolog 4 (Pc class homolog, Drosophila), anticorps CBX4, anticorps Cbx4, anticorps cbx4.S, anticorps cbx4
- Sujet
- Chromobox homolog 4 (CBX4 or Pc2) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression pf PcG proteins have been associated with cancer. CBX4 is a part of the cellular memory system that is responsible for the inheritance of gene activity by progeny cells. CBX4 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain. It was reported that Pc2 is involved in sumoylation process by recruiting SUMO E1 and E2, and Pc2 is actually SUMO E3 during sumoylation events. CBX4 expression is ubiquitous.Synonyms: Chromobox protein homolog 4, E3 SUMO-protein ligase CBX4, Polycomb 2 homolog
- Poids moléculaire
- 61228 Da
- ID gène
- 8535, 9606
- UniProt
- O00257
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