NR4A1 anticorps (pSer351)

N° du produit ABIN358306

Détail du produit anti-NR4A1 anticorps

Antigène: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Épitope: pSer351

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR4A1 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Specificité: This antibody detects NAK1/NR4A1 pSer351 . Predicted to cross react with Mouse (100 % Antigen Homology).

Purification: Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S351 of human NR4A1.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Dot Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur NR4A1

Antigène: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Autre désignation: NAK1 (NR4A1 Produits)

Synonymes: anticorps GFRP1, anticorps HMR, anticorps N10, anticorps NAK-1, anticorps NGFIB, anticorps NP10, anticorps NUR77, anticorps TR3, anticorps NGFI-B, anticorps Gfrp, anticorps Hbr-1, anticorps Hbr1, anticorps Hmr, anticorps TIS1, anticorps nur77, anticorps Ngfi-b, anticorps Nur77, anticorps nuclear receptor subfamily 4 group A member 1, anticorps nuclear receptor subfamily 4, group A, member 1, anticorps NR4A1, anticorps Nr4a1

Sujet: NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.Synonyms: Early Response Protein NAK1, GFRP1, HMR, N10, NR4A1, NUR77, Orphan Nuclear Receptor HMR, ST-59, TR3 Orphan Receptor

Poids moléculaire: 64463 Da

ID gène: 3164, 9606

UniProt: P22736

Pathways: Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway