ROR2 anticorps
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- Antigène Voir toutes ROR2 Anticorps
- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ROR2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to ROR2.
- Purification
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Immunogène
- This antibody is generated from rabbits immunized with a recombinant protein of human ROR2.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ROR2 Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
- Autre désignation
- ROR2 (ROR2 Produits)
- Synonymes
- anticorps BDB, anticorps BDB1, anticorps NTRKR2, anticorps Ntrkr2, anticorps mRor2, anticorps ROR2, anticorps bdb, anticorps bdb1, anticorps Xror2, anticorps ntrkr2, anticorps MGC97773, anticorps LOC100219935, anticorps ror2, anticorps xror2, anticorps receptor tyrosine kinase like orphan receptor 2, anticorps receptor tyrosine kinase-like orphan receptor 2, anticorps receptor tyrosine kinase like orphan receptor 2 L homeolog, anticorps ROR2, anticorps Ror2, anticorps ror2, anticorps ror2.L
- Sujet
- ROR2 is a tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. This Type I membrane protein is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Defects in ROR2 are a cause of brachydactyly type B1 (BDB1). BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent. Both fingers and toes are affected. The thumbs and big toes are usually deformed. Defects in ROR2 are a cause of recessive Robinow syndrome (RRS). RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a dysmorphic facial appearance. The protein contains 1 frizzled (FZ) domain, 1 immunoglobulin-like C2-type domain, and 1 kringle domain.Synonyms: NTRKR2, Tyrosine-protein kinase transmembrane receptor ROR2
- ID gène
- 4920, 9606
- UniProt
- Q01974
- Pathways
- Signalisation RTK, Signalisation WNT
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