NTRK3 anticorps (N-Term)

N° du produit ABIN359954

Détail du produit anti-NTRK3 anticorps

Antigène: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NTRK3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to TRKC.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TRKC.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur NTRK3

Antigène: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Autre désignation: TrkC (NTRK3 Produits)

Synonymes: anticorps TRKC, anticorps gp145(trkC), anticorps trkC, anticorps AW125844, anticorps Ntrk3_tv3, anticorps TrkC, anticorps neurotrophic receptor tyrosine kinase 3, anticorps neurotrophic tyrosine kinase, receptor, type 3, anticorps NTRK3, anticorps Ntrk3

Sujet: TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.Synonyms: GP145-TrkC, NT-3 growth factor receptor, NTRK3, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase

ID gène: 4916, 9606

UniProt: Q16288

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway, Regulation of Cell Size