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c-MET anticorps (pTyr1234)

Cet anticorps anti-c-MET est un anticorps Lapin Polyclonal détectant c-MET dans WB. Adapté pour Humain, Souris et Rat.
N° du produit ABIN362272

Aperçu rapide pour c-MET anticorps (pTyr1234) (ABIN362272)

Antigène

Voir toutes c-MET (MET) Anticorps
c-MET (MET) (Met Proto-Oncogene (MET))

Reactivité

  • 221
  • 127
  • 93
  • 5
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 191
  • 38
  • 4
  • 3
  • 2
Lapin

Clonalité

  • 181
  • 53
  • 2
Polyclonal

Conjugué

  • 123
  • 19
  • 10
  • 10
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Cet anticorp c-MET est non-conjugé

Application

  • 150
  • 93
  • 42
  • 32
  • 30
  • 19
  • 15
  • 14
  • 14
  • 9
  • 8
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 40
    • 27
    • 27
    • 24
    • 12
    • 11
    • 9
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1234

    Specificité

    The antibody detects endogenous level of Met only when phosphorylated at tyrosine 1234.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    Immunogène

    Peptide sequence around phosphorylation site of pTyr1234 (K-E-Y (p) -Y-S) derived from Human Met. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

    Isotype

    IgG
  • Indications d'application

    Western blotting: 1:500-1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Antigène

    c-MET (MET) (Met Proto-Oncogene (MET))

    Autre désignation

    Met

    Sujet

    Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.

    Poids moléculaire

    156 kDa

    NCBI Accession

    NP_000236

    UniProt

    P08581

    Pathways

    Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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