×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
NFKBIA anticorps (AA 30-34, AA 34-38)
NFKBIA
Reactivité: Humain, Souris, Rat
WB, IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-NFKBIA anticorps
(cache)
Antigène
Voir toutes NFKBIA Anticorps
NFKBIA
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
Épitope
Tous les épitopes à travers NFKBIA Anticorps.
AA 30-34, AA 34-38
Reactivité
Toutes les réactivités sur NFKBIA Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur NFKBIA Anticorps
Lapin
Clonalité
Toutes les clonalités sur NFKBIA Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers NFKBIA Anticorps
Cet anticorp NFKBIA est non-conjugé
Application
Tous les applications à travers NFKBIA Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Specificité
The antibody detects endogenous level of total IkB-a protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen. Specificity/Sensitivity IΰB-α (Ab-32/36) antibody detects endogenous levels of total IΰB-α protein.
Immunogène
Peptide sequence around AA 30-34, 34-38 (H-D-S-G-L- D-S -M-K) derived from Human IkB-a. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotype
IgG
Top Product
Discover our top product NFKBIA Anticorps primaire
Alternatives
(show)
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-120) antibody
NFKBIA
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet
WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
(cache)
Indications d'application
Western blotting: 1:500-1:1000 Immunohistochemistry: 1:50-1:100 Immunofluorescence: 1:100-1:200
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Détails sur NFKBIA
(cache)
Antigène
NFKBIA
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
Autre désignation
IkappaB-alpha (NFKBIA Produits )
Synonymes
anticorps IKBA, anticorps MAD-3, anticorps NFKBI, anticorps AI462015, anticorps Nfkbi, anticorps RL/IF-1, anticorps ECI-6/IKBA, anticorps NFKBIA, anticorps ikbaB, anticorps wu:fb81f08, anticorps zgc:56666, anticorps zgc:77616, anticorps ikbaA, anticorps wu:fj16a07, anticorps zgc:85769, anticorps NFKB inhibitor alpha, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a, anticorps NFKBIA, anticorps Nfkbia, anticorps nfkbiab, anticorps nfkbiaa
Sujet
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.
Poids moléculaire
39 kDa
NCBI Accession
NP_065390
UniProt
P25963
Pathways
Signalisation NF-kappaB , TCR Signaling , Signalisation TLR , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Maintenance of Protein Location , Hepatitis C , Protein targeting to Nucleus , Toll-Like Receptors Cascades , BCR Signaling
Vus récemment
(cache)