FOXA2 anticorps (C-Term)

N° du produit ABIN374335

Détail du produit anti-FOXA2 anticorps

Antigène: FOXA2 (Forkhead Box A2 (FOXA2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXA2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-GVYSRPIMNS S

Specificité: This antibody detects FOXA2 at C-term. It is expected to recognise both reported isoforms.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Syntehtic peptide from the C-Terminus of the protein sequence according to NP_068556.2, NP_710141.1. Genename: FOXA2

Information d'application

Indications d'application: Peptide ELISA: Limit dilution 1: 2000. Western blot: 0.5 μg/mL. Approx 60-65 kDa band observed in Human Liver lysate (predictedMW of 55 kDa according to NP_068556 and NP_710141).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FOXA2

Antigène: FOXA2 (Forkhead Box A2 (FOXA2))

Autre désignation: FOXA2 / HNF3B (FOXA2 Produits)

Synonymes: anticorps hnf3b, anticorps tcf3b, anticorps hnf3beta, anticorps hnf3-beta, anticorps FOXA2, anticorps HNF3B, anticorps TCF3B, anticorps HNF-3B, anticorps ax, anticorps axl, anticorps fkd1, anticorps ik:tdsubc_2g8, anticorps tdsubc_2g8, anticorps wu:fe05g04, anticorps xx:tdsubc_2g8, anticorps FoxA2-A, anticorps FoxA2a, anticorps xFD-3, anticorps xbeta-1, anticorps HNF-3b, anticorps HNF3-beta, anticorps HNF3beta, anticorps Hnf-3b, anticorps Hnf3b, anticorps Tcf-3b, anticorps Tcf3b, anticorps HNF-3BETA, anticorps forkhead box A2, anticorps forkhead box A2 L homeolog, anticorps foxa2, anticorps FOXA2, anticorps foxa2.L, anticorps Foxa2

Sujet: FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporatic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.Synonyms: HNF-3-beta, HNF-3B, Hepatocyte nuclear factor 3-beta, TCF3B, Transcription factor 3B

ID gène: 3170

NCBI Accession: NP_068556

UniProt: Q9Y261

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process