DKK1 anticorps (C-Term)

N° du produit ABIN374460

Détail du produit anti-DKK1 anticorps

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Épitope: C-Term

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DKK1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to Dickkopf-1.

Réactivité croisée (Details): Species reactivity (expected):Rat, Canine, Bovine, Porcine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence CDHHQASNSSRLHT, from the C Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/128000. Western blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-DKK1 (ABIN374460)

Niessner, Kosnopfel, Sinnberg, Beck, Krieg, Wanke, Lasithiotakis, Bonin, Garbe, Meier: "Combined activity of temozolomide and the mTOR inhibitor temsirolimus in metastatic melanoma involves DKK1." dans: Experimental dermatology, Vol. 26, Issue 7, pp. 598-606, (2018) (PubMed).

Détails sur DKK1

Antigène: DKK1 (Dickkopf Homolog 1 (DKK1))

Autre désignation: Dickkopf-1 (DKK1 Produits)

Synonymes: anticorps DKK-1, anticorps SK, anticorps AI414495, anticorps SGY, anticorps SGY-1, anticorps SGY1, anticorps Soggy, anticorps mSgy, anticorps dkk1, anticorps dkk, anticorps dkk-1, anticorps xdkk1, anticorps Xdkk-1, anticorps Dickkopf1, anticorps dickkopf-1, anticorps mdkk-1, anticorps dkk1-A, anticorps dickkopf WNT signaling pathway inhibitor 1, anticorps dickkopf like acrosomal protein 1, anticorps dickkopf-related protein 1, anticorps dickkopf-like 1, anticorps dickkopf WNT signaling pathway inhibitor 1b, anticorps dickkopf protein, anticorps dickkopf WNT signaling pathway inhibitor 1 S homeolog, anticorps DKK1, anticorps Dkk1, anticorps DKKL1, anticorps LOC100228789, anticorps Dkkl1, anticorps dkk1b, anticorps dkk1, anticorps dickkopf, anticorps dkk1.S

Sujet: DKK1 is an inhibitor of the Wnt signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.Synonyms: DKK-1, DKK1, Dickkopf-related protein 1, SK

ID gène: 22943

NCBI Accession: NP_036374

UniProt: O94907

Pathways: Signalisation WNT, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation