TCF3 anticorps (Internal Region)

N° du produit ABIN374866

Détail du produit anti-TCF3 anticorps

Antigène: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF3 est non-conjugé

Application: Western Blotting (WB)

Séquence: C-KAPRARTSPD EDED

Specificité: This antibody detects TCF3 / E2A.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_003191.1 Genename: TCF3

Information d'application

Indications d'application: Peptide ELISA: antibody detection limit dilution 1: 128000. Western blot: 0.01-0.03 μg/mL. Approx 75 kDa band observed in lysates of cell line Daudi(calculated MW of 67.5 kDa according to NP_003191.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur TCF3

Antigène: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Autre désignation: TCF3 / E2A (TCF3 Produits)

Synonymes: anticorps E2A, anticorps E47, anticorps ITF1, anticorps TCF-3, anticorps VDIR, anticorps bHLHb21, anticorps tcf3a, anticorps zgc:113045, anticorps A1, anticorps AA408400, anticorps ALF2, anticorps AW209082, anticorps E12, anticorps E12/E47, anticorps ME2, anticorps Pan1, anticorps Pan2, anticorps Tcfe2a, anticorps bhlhb21, anticorps e2a, anticorps itf1, anticorps tcfe2a, anticorps vdir, anticorps xtcf-3, anticorps xtcf3, anticorps G12, anticorps TCF7L1, anticorps XE3, anticorps transcription factor 3, anticorps transcription factor 3b, anticorps transcription factor 3 L homeolog, anticorps transcription factor E2a, anticorps TCF3, anticorps tcf3b, anticorps Tcf3, anticorps tcf3.L, anticorps tcfe2a

Sujet: Heterodimers between TCF3 and tissue specific basic helix loop helix (bHLH) proteins play major roles in determining tissue specific cell fate during embryogenesis, like muscle or early B cell differentiation. Dimers bind DNA on E box motifs: 5' CANNTG 3'. Binds to the kappa E2 site in the kappa immunoglobulin gene enhancer.Synonyms: ITF-1, ITF1, Immunoglobulin enhancer-binding factor E12/E47, Immunoglobulin transcription factor 1, Kappa-E2-binding factor, TCF-3, Transcription factor 3, Transcription factor E2-alpha, Transcription factor ITF-1

ID gène: 6929

NCBI Accession: NP_001129611

UniProt: P15923

Pathways: Signalisation WNT, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response