CRHR1 anticorps (Internal Region)

N° du produit ABIN374874

Détail du produit anti-CRHR1 anticorps

Antigène: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Épitope: AA 107-117, Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CRHR1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Séquence: C-NEEKKSKVHY H

Specificité: This antibody detects CRHR1.

Réactivité croisée (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Human, Mouse.

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_004373.2 Genename: CRHR1

Information d'application

Indications d'application: Peptide ELISA: antibody detection limit dilution 1: 32000. Western blot: 0.1-0.3 μg/mL. Approx 60-70 kDa band observed in human brain (cerebellum)and human colon lysates (calculated MW of 47.0 kDa according to NP_004373.2). Theobserved molecular weight corresponds to earlier findings in literature with differentantibodies (Xu et al, Mol Pharmacol.2001 Mar,59(3): 485-92, PMID: 11179443) . Immunofluorescence: 2 μg/mL when incubated at 4 °C for 40h (mouse brain).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CRHR1

Antigène: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Autre désignation: CRHR1 (CRHR1 Produits)

Synonymes: anticorps CRF-R, anticorps CRF-R-1, anticorps CRF-R1, anticorps CRF1, anticorps CRFR-1, anticorps CRFR1, anticorps CRH-R-1, anticorps CRH-R1, anticorps CRH-R1h, anticorps CRHR, anticorps CRHR1L, anticorps CRHR1f, anticorps Crhr, anticorps crhr1, anticorps crhr1-A, anticorps CRHR1, anticorps CRHR1-IT1-CRHR1, anticorps MGC57346-CRHR1, anticorps corticotropin releasing hormone receptor 1, anticorps corticotropin releasing hormone receptor 1, gene 2 S homeolog, anticorps corticotropin-releasing factor receptor 1, anticorps LINC02210-CRHR1 readthrough, anticorps CRHR1, anticorps Crhr1, anticorps crhr1.2.S, anticorps LOC610380, anticorps LOC100065598, anticorps LINC02210-CRHR1, anticorps crhr1

Sujet: CRF1 is a receptor for corticotropin releasing factor. It shows high affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.Synonyms: CRF-R, CRF1, CRFR, CRFR1, CRH-R 1, CRHR, CRHR-1, Corticotropin-releasing factor receptor 1, Corticotropin-releasing hormone receptor 1

ID gène: 1394

NCBI Accession: NP_001138618

UniProt: P34998

Pathways: Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity