GCH1 anticorps (Internal Region)
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- Antigène Voir toutes GCH1 Anticorps
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GCH1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody is expected to recognize all four isoforms.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography
- Immunogène
- Peptide with sequence C-GKVHIGYLPNKQ, from the internal region of the protein sequence Genename: GCH1
- Top Product
- Discover our top product GCH1 Anticorps primaire
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- Indications d'application
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Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
- Abstract
- GCH1 Produits
- Synonymes
- anticorps DYT14, anticorps DYT5, anticorps DYT5a, anticorps GCH, anticorps GTP-CH-1, anticorps GTPCH1, anticorps HPABH4B, anticorps GTP-CH, anticorps GTPCH, anticorps Gch, anticorps MGC89622, anticorps gch1a, anticorps wu:fc16b10, anticorps zgc:195269, anticorps GTP cyclohydrolase 1, anticorps GTP cyclohydrolase 1-like, anticorps GCH1, anticorps Gch1, anticorps gch1, anticorps Weevi_1190, anticorps Halhy_0838, anticorps Sinme_1220, anticorps Sphch_1077, anticorps LOC100136794
- Sujet
- GCH1 is a member of the GTP cyclohydrolase family. It is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.Synonyms: DYT5, GCH, GTP cyclohydrolase I, GTP-CH-I
- ID gène
- 2643, 9606
- UniProt
- P30793
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