PDGFB anticorps (C-Term)

N° du produit ABIN388460

Détail du produit anti-PDGFB anticorps

Antigène: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Épitope: AA 212-241, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDGFB est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PDGFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-241 amino acids from the C-terminal region of human PDGFB.

Clone: RB2203

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur PDGFB

Antigène: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Autre désignation: PDGFB (PDGFB Produits)

Synonymes: anticorps PDGF-2, anticorps PDGF2, anticorps SIS, anticorps SSV, anticorps c-sis, anticorps pdgf2, anticorps sis, anticorps si:ch211-79m20.1, anticorps si:dkey-261d11.1, anticorps PDGF-B, anticorps Sis, anticorps platelet derived growth factor subunit B, anticorps platelet-derived growth factor beta polypeptide, anticorps platelet derived growth factor subunit B S homeolog, anticorps platelet-derived growth factor beta polypeptide a, anticorps platelet derived growth factor, B polypeptide, anticorps PDGFB, anticorps pdgfb.S, anticorps pdgfba, anticorps Pdgfb

Sujet: PDGFB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor alpha polypeptide, where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor.

Poids moléculaire: 27283

ID gène: 5155

NCBI Accession: NP_002599, NP_148937

UniProt: P01127

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling