RFC5 anticorps (AA 170-200)

N° du produit ABIN389314

Détail du produit anti-RFC5 anticorps

Antigène: RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))

Épitope: AA 170-200

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFC5 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This RFC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-200 amino acids from the Central region of human RFC5.

Clone: RB17319

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur RFC5

Antigène: RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))

Autre désignation: RFC5 (RFC5 Produits)

Synonymes: anticorps zgc:110313, anticorps 2610020K06Rik, anticorps 2610209F07Rik, anticorps 36.5kDa, anticorps 36kDa, anticorps Recc5, anticorps RFC36, anticorps replication factor C (activator 1) 5, anticorps replication factor C subunit 5, anticorps replication factor C subunit 5 L homeolog, anticorps rfc5, anticorps Rfc5, anticorps RFC5, anticorps rfc5.L

Sujet: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. RFC5 is the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system.

Poids moléculaire: 38497

ID gène: 5985

NCBI Accession: NP_001123584, NP_031396, NP_853556

UniProt: P40937

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA