NTRK3 anticorps (N-Term)

N° du produit ABIN392066

Détail du produit anti-NTRK3 anticorps

Antigène: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Épitope: AA 31-61, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NTRK3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Pr, M, Pig, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This TRKC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-61 amino acids from the N-terminal region of human TRKC.

Clone: RB1539

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur NTRK3

Antigène: NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))

Autre désignation: TRKC (NTRK3 Produits)

Synonymes: anticorps TRKC, anticorps gp145(trkC), anticorps trkC, anticorps AW125844, anticorps Ntrk3_tv3, anticorps TrkC, anticorps neurotrophic receptor tyrosine kinase 3, anticorps neurotrophic tyrosine kinase, receptor, type 3, anticorps NTRK3, anticorps Ntrk3

Sujet: TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.

Poids moléculaire: 94428

ID gène: 4916

NCBI Accession: NP_001012338, NP_002521

UniProt: Q16288

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway, Regulation of Cell Size