WNT1 anticorps (Internal Region)

N° du produit ABIN401405

Détail du produit anti-WNT1 anticorps

Antigène: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Singe, Opossum

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts with Wnt1 protein.

Réactivité croisée (Details): Species reactivity (expected):Rat, Bovine, Canine, Macaque, Opossum.
Species reactivity (tested):Human, Mouse.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide corresponding to an internal region of Human Wnt1 protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/25,000. Western Blot: 1/1,500 - 1/6,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.38 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur WNT1

Antigène: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Autre désignation: WNT1 (WNT1 Produits)

Synonymes: anticorps Xint-1, anticorps Xwnt1, anticorps int-1, anticorps int1, anticorps wnt-1, anticorps wnt1-a, anticorps Int-1, anticorps Wnt-1, anticorps sw, anticorps swaying, anticorps BMND16, anticorps INT1, anticorps OI15, anticorps Int1, anticorps WNT-1, anticorps sb:eu647, anticorps zgc:194464, anticorps zgc:194478, anticorps WNT1, anticorps Wnt family member 1, anticorps Wnt family member 1 L homeolog, anticorps wingless-type MMTV integration site family, member 1, anticorps WNT1, anticorps wnt1.L, anticorps Wnt1, anticorps wnt1

Sujet: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt1 (Wingless-type MMTV integration site family member 1) is a member of the WNT gene family. It is highly conserved in evolution and the protein encoded by this gene is known to be 98 % identical to mouse Wnt1 protein at the amino acid level. Studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. Wnt1 is secreted as an extracellular matrix protein.Synonyms: INT-1, INT1, Proto-oncogene protein Wnt-1

ID gène: 7471

NCBI Accession: NP_005421

UniProt: P04628

Pathways: Signalisation WNT, Dopaminergic Neurogenesis