ROR1 anticorps

N° du produit ABIN462403

Détail du produit anti-ROR1 anticorps

Antigène: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ROR1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Human ROR1. This antibody is expected to recognize isoform 1 (NP_005003.2) only.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Lizard (93%) Turkey, Chicken (87%) Platypus (80%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-GNKSQKPYKIDSKQA from the C-terminus (near) of human ROR1 (NP_005003.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%), Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Lizard (93%), Turkey, Chicken (87%), Platypus (80%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (3 - 6 μg/mL), Peptide-ELISA

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3-6 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur ROR1

Antigène: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Autre désignation: ROR1 (ROR1 Produits)

Synonymes: anticorps NTRKR1, anticorps dJ537F10.1, anticorps 2810404D04Rik, anticorps Ntrkr1, anticorps mRor1, anticorps RGD1559469, anticorps ROR1, anticorps fi34e02, anticorps si:dkey-209n16.1, anticorps wu:fi34e02, anticorps receptor tyrosine kinase like orphan receptor 1, anticorps receptor tyrosine kinase-like orphan receptor 1, anticorps ROR1, anticorps Ror1, anticorps ror1

Sujet: Name/Gene ID: ROR1
Subfamily: Trk/Ror
Family: Protein Kinase

Synonyms: ROR1, DJ537F10.1, NTRKR1, Protein tyrosine kinase t-ror1

ID gène: 4919

NCBI Accession: NP_005003

UniProt: Q01973

Pathways: Signalisation RTK, Signalisation WNT, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha