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Collagen IV anticorps

COL4 Reactivité: Humain, Souris, Rat IHC, IF Hôte: Souris Monoclonal unconjugated
N° du produit ABIN5610391
  • Antigène Voir toutes Collagen IV (COL4) Anticorps
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    Reactivité
    • 88
    • 43
    • 40
    • 23
    • 16
    • 10
    • 5
    • 2
    Humain, Souris, Rat
    Hôte
    • 57
    • 26
    • 12
    Souris
    Clonalité
    • 68
    • 27
    Monoclonal
    Conjugué
    • 45
    • 10
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp Collagen IV est non-conjugé
    Application
    • 61
    • 45
    • 30
    • 29
    • 27
    • 26
    • 26
    • 24
    • 17
    • 9
    • 9
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Fonction
    Collagen IV is a protein encoded by the COL4A1 gene which is approximately 160,6 kDa. Collagen IV is secreted into the extracellular space. It is involved in collagen chain trimerization, the integrin pathway, ERK signalling and focal adhesion. It is the major structural component of glomerular basement membranes and forms a chicken-wire meshwork together with laminins, proteoglycans and entactin/nidogen. It specifically inhibits endothelial cell proliferation, migration and tube formation. Collagen IV is expressed in the nervous system, liver, lung, heart and kidney. Mutations in the COL4A1 gene may result in the tortuosity of retinal arteries. STJ98907 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous Collagen IV protein.
    Specificité
    The antibody detects endogenous Collagen IV protein.
    Attributs du produit
    Mouse Monoclonal to Collagen IV.
    Purification
    The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogène
    synthetic peptide derived from Collagen IV.
    Top Product
    Discover our top product COL4 Anticorps primaire
  • Indications d'application
    IF 1:50-200
    IHC-P 1:50-300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • Antigène
    Collagen IV (COL4) (Collagen, Type IV (COL4))
    Autre désignation
    Collagen IV (COL4 Produits)
    Synonymes
    anticorps collagen, type IV, anticorps Let-2
    Poids moléculaire
    161kDa
    UniProt
    P02462
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