Collagen IV anticorps
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- Antigène Voir toutes Collagen IV (COL4) Anticorps
- Collagen IV (COL4) (Collagen, Type IV (COL4))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Collagen IV est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Fonction
- Collagen IV is a protein encoded by the COL4A1 gene which is approximately 160,6 kDa. Collagen IV is secreted into the extracellular space. It is involved in collagen chain trimerization, the integrin pathway, ERK signalling and focal adhesion. It is the major structural component of glomerular basement membranes and forms a chicken-wire meshwork together with laminins, proteoglycans and entactin/nidogen. It specifically inhibits endothelial cell proliferation, migration and tube formation. Collagen IV is expressed in the nervous system, liver, lung, heart and kidney. Mutations in the COL4A1 gene may result in the tortuosity of retinal arteries. STJ98907 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous Collagen IV protein.
- Specificité
- The antibody detects endogenous Collagen IV protein.
- Attributs du produit
- Mouse Monoclonal to Collagen IV.
- Purification
- The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- synthetic peptide derived from Collagen IV.
- Top Product
- Discover our top product COL4 Anticorps primaire
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- Indications d'application
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IF 1:50-200
IHC-P 1:50-300 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Antigène
- Collagen IV (COL4) (Collagen, Type IV (COL4))
- Autre désignation
- Collagen IV (COL4 Produits)
- Synonymes
- anticorps collagen, type IV, anticorps Let-2
- Poids moléculaire
- 161kDa
- UniProt
- P02462
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